Your main tasks

  • Expression and purification of recombinant proteins
  • Develop and perform enzymatic (determine enzyme activity and kinetics) and substrate
    binding assays independently or with other team members as instructed
  • Screen small molecule ligands in microplate-based assay formats to drive SAR
    relationships on purified protein using manual and automated systems
  • Organize and present to the team experimental results; maintain clear experimental
    records using ELN
  • Maintain clear records of experimental work and be able to organize, report and
    communicate results

Your qualifications

  • BSc/MSc/apprenticeship in biochemistry, enzymology, pharmacology, or related field
  • 2+ years of experience in biotech and/or pharmaceutical companies
  • Must have good experience with biochemical assays, enzyme kinetics and substrate
    binding assays
  • Must have hands-on experience developing and running 96/384-well microplate-based
    biochemical and kinetic-based assay technologies (e.g., DSF/TSA, fluorescence-based
    assays, luminescence)
  • A strong preference will be given to candidates with hands-on experience with
    recombinant protein expression and purification

Who needs your support?

Our client is a privately held drug discovery company based in Basel, Switzerland. They focus on drugging key molecular targets involved in DNA Replication Stress, which constitutes an exciting and innovative approach in the development of novel anticancer drugs. This is an exciting opportunity to become an integral part of an innovative and dynamic start-up company.

Benefits

5 weeks vacation

Annual Company Event

Bonus payment

Corporate shares

Startup culture

Well connected office

Are you interested?

If we have raised your interest, we look forward to hearing from you.

Doris Fink

+41 44 330 03 31

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